Prof. Ruben Martin

Catalysis

Group Leader:

Ruben Martin, ICREA Professor

Postdoctoral Researchers:

Ciro Romano / Jacob Davies / Riccardo Salvatore Mega / Robert Freund / Matthew Wakeling / Roman Abrams / Santosh Gadekar / Jesús Rodrigálvarez / Franz-Lucas Haut / Nahury Yamile Castellanos / Tomas Gil / Liangliang Zhang

PhD students:

Fei Cong / Bradley Higginson / Craig Day / Laura Talavera / Carlota Odena / Xinyang Lyu / Dmitry Zimin / Wenjun Yue / Julien Lyonett / Jinhong Chen / Julia Ordóñez / Adrian Brenes / Huihui Zhang / Hao Wang / Filip Meger / Yu-biao Tian

Master students:

Joan Vicent Estornell / Clarence Tan Kang Lek

Lab technician:

David Sádaba

Visiting Researchers:

Ryan McGuire / Kim Saskia Mühlfenzl / Vu Duc Ha Phan

Summary

The research of Prof. Martin focuses on discovering the potential of catalytic functionalization of raw materials for the synthesis of valuable compounds from simple and abundant precursors. They have contributed extensively to the catalytic functionalization of C-O and C-H bonds, as well as to the fixation of CO2 to organic matter. They have described a catalytic technology capable of fixing carbon dioxide in saturated and unsaturated hydrocarbons to prepare fatty acids, key parts in the manufacture of polymers, detergents, cosmetics, and pharmaceuticals.

Publications

Trifluoromethylation of Carbonyl and Unactivated Olefin Derivatives by C(sp3)–C Bond Cleavage
Cong, F.; Mega, R. S.; Chen, J.; Day, C. S.; Martin, R.
Angew. Chem. Int. Ed. 2022, 135 (5)

Ni-Catalyzed Oxygen Transfer from N2O onto sp3-Hybridized Carbons
Ni, S.; Le Vaillant, F.; Mateos-Calbet, A.; Martin, R.; Cornella, J.
Am. Chem. Soc 2022, 144 (40)

Nickel-Catalyzed Site-Selective Intermolecular C(sp3)−H Amidation
Chen, J.; Wang, H.; Day, C. S.; Martin, R.
Angew. Chem. Int. Ed. 2022, 61 (50)

MORE PUBLICATIONS

Ni-Catalyzed Site-Selective Hydrofluoroalkylation of Terminal and Internal Olefins
Yue, W. J.; Martin, R.
ACS Catal. 2022, 12, 12132–12137

Reductive Elimination from Sterically Encumbered Ni–Polypyridine Complexes
Day, C. S.; Ton, S. J.; McGuire, R. T.; Foroutan-Nejad, C.; Martin, R.
Organometallics 2022

Room-Temperature-Stable Magnesium Electride via Ni(II) Reduction
Day, C. S.; Dat Do, C.; Odena, C.; Benet-Buchholz, J.; Xu, L., Foroutan-Nejad, C.; Hopmann, K. H.; Martin, R.
J. Am. Chem. Soc. 2022, 144 (29), 13109–13117

Catalytic Hydrodifluoroalkylation of Unactivated Olefins
Yue, W. J.; Day, C. S.; Brenes Rucinski, A. J.; Martin, R.
Org. Lett. 2022, 24 (28), 5109–5114

Conformational Flexibility as a Tool for Enabling Site-Selective Functionalization of Unactivated sp3 C–O Bonds in Cyclic Acetals
Romano, C.; Talavera, L.; Gómez-Bengoa, E.; Martin, R.
Am. Chem. Soc. 2022

Dihydroquinazolinones as adaptative C(sp3) handles in arylations and alkylations via dual catalytic C–C bond-functionalization
Lv, X. Y.; Abrams, R.; Martin, R.
Nat. Commun. 2022, 13, 2394

Redox-Neutral Ni-Catalyzed sp3 C–H Alkylation of α-Olefins with Unactivated Alkyl Bromides
Buendia, M. K.; Higginson, B.; Kegnæs, S.; Kramer, S.; Martin, R.
ACS Catal. 2022, 12, 3815–3820

Enantioselective Deaminative Alkylation of Amino Acid Derivatives with Unactivated Olefins
Sun, S. Z.; Cai, Y. M.; Zhang, D. L.; Wang, J. B.; Yao, H. Q.; Rui, X. Y.; Martin, R.; Shang, M.
J. Am. Chem. Soc. 2022, 144 (3), 1130–1137

Defunctionalization of sp3 C–Heteroatom and sp3 C–C Bonds Enabled by Photoexcited Triplet Ketone Catalysts
Gu, Y.; Yin, H.; Wakeling, M.; An, J.; Martin, R.
ACS Catal. 2022, 12, 1031–1036

Pd-catalyzed Arylation of 1,2-Amino Alcohol Derivatives via beta-Carbon Elimination
Sau, M.; Martin, R.; Pericàs, M. A.
Synlett 2022, 33 (1), 52-56

Projects

NOVOFLAT
Escaping from Flatland by “de novo” Catalytic Decarboxylation Techniques
ERC Advanced Grant | Ref: 883756

CO2PERATE
Cooperation towards a sustainable chemical industry
MSCA ITN | Ref: 859910 Web page

NICK-BOND
Nickel-catalyzed bond-formation reactions with native functional groups
Ministerio | Ref: PGC2018-096839-B-I00

CAT-NAT
Formación enlaces sp3 carbono-carbono y carbono-heteroatomo mediante funcionalización catalítica de grupos nativos
Ministerio | Ref: PID2021-123801NB-I00 

CATINERT
Grup d’Activació Catalítica d’Enllaços Inerts
AGAUR | Ref: SGR 938

Theses Supervised

Craig Day
July 1, 2022
Universitat Rovira i Virgili
More is Different Modern Computational Modeling for Heterogeneous Catalysis

Bradley Higginson
November 17, 2022
Universitat Rovira i Virgili
Catalytic transformations enabled by dual nickel-photoredox manifolds

 

Features

Three ICIQers participate in the 71st Nobel Laureate Meeting in Chemistry
https://www.iciq.org/three-iciqers-participate-in-the-71st-nobel-laureate-meeting-in-chemistry/

Cross-coupling ketones: adding flexibility to the synthetic chemistry toolbox
https://www.iciq.org/cross-coupling-ketones-adding-flexibility-to-the-synthetic-chemistry-toolbox/