Prof. Pau Ballester

Functional Molecular Assemblies / Materials

Group Leader:

Pau Ballester, ICREA Professor

Scientific Coordinator:

Gemma Aragay

Postdoctoral Researchers:

Felipe Sierra (since Mar.), Evgeny Bulatov, Eva González, Karen de la Vega

PhD Students:

Felipe Sierra (until Feb.) / Pedro Ferreira (until June) / Chiara Mirabella (until Sep) / Andrea Rivoli / Yifan Li / Hayley Kay Frost (until Sep), Esteban A. Valencia

 

Summary

The Ballester group works in the areas of organic chemistry (making molecules) and physical organic chemistry (studying how the molecules interact with each other). Their current research focuses on the design, synthesis, study, and characterization of functional molecular aggregates. Prof. Ballester considers himself an architect / molecular engineer. In the group, they study matter but also produce matter and new materials. The group applies molecular self-assembly processes as a methodology for constructing large and functional interconnected structures, such as molecular machines, or molecular sensors and devices. The group also applies the developed receptors as carriers for anions and amino acids across liposomal membranes.

Their second area of ​​interest is the design and application of molecular containers, cages and capsules. These are molecular or supramolecular architectures with an internal cavity large enough to include or encapsulate other molecules. The cavities of the molecular containers are exploited for the stabilization of reactive molecules or in the mediation of chemical reactions among others.

Publications

Novel nandrolone aptamer for rapid colorimetric detection of anabolic steroids
Shkembia, X.; Botero, M. L.; Skouridou, V.; Jauset-Rubio, M.; Svobodova, M.; Ballester, P.; Bashammak, A. S.; El-Shahawic, M. S.; Alyoubic, A. O.; O’Sullivan, C. K.
Anal. Biochem. 2022, 658, 114937 

Influence of the solvent in the self-assembly and binding properties of [1 + 1] tetra-imine bis-calix[4]pyrrole cages
Mirabella, C. F. M.; Aragay, G.; Ballester, P.
Chem. Sci. 2022, 186-195

Potentiometric detection of creatinine in the presence of nicotine: Molecular recognition, sensing and quantification through multivariate regression
Corbaad, A.; Sierra, A. F.; Blondeau, P.; Giussani, B.; Riu, J.; Ballester, P.; Andrade, F. J.
Talanta 2022, 246, 123473

 

MORE PUBLICATIONS

Supramolecular approaches to mediate chemical reactivity
Ballester, P.; Wang, Q.; Gaeta, C.
Beilstein J. Org. Chem. 2022, 1463–1465

Chloride Binding Properties of a Macrocyclic Receptor Equipped with an Acetylide Gold(I) Complex: Synthesis, Characterization, Reactivity, and Cytotoxicity Studies
Rivoli, A.; Aragay, G., Gimeno, M. C.; Ballester, P.
Inorganics 2022, 10 (7), 95

A Dinuclear Metallobridged Super Aryl-Extended Calix[4]pyrrole Cavitand
Sun, Q.; Escobar, L.; Ballester, P.
Angew. Chem. Int. Ed. 2022, 61 (22), e202202140

Projects

OL-Future: Solar Catalysis for a Renewable Energy Future
Ministerio de Ciencia e Innovación | Ref: PLEC2021-007906

COMPOFUN: Molecular containers with polar cavities and versatile functions
Ministerio de Ciencia e Innovación | Ref: PID2020-114020GB-100

NOAH: Network of Functional Molecular Containers with Controlled Switchable Abilities
MSCA IF | Ref: 765297

Química supramolecular interdisciplinar
AGAUR | Ref: 2021SGR00851

MAKI-2: Real-time sensing of diagnostically-relevant biomarkers in urine for the monitoring of acute kidney injury.
BIST.

 

Theses Supervised

Andrés Felipe Sierra Ramos
February 24, 2022
Universitat Rovira i Virgili
Calix[4]pyrrole containers as molecular sensors

Pedro Miguel Mendonça Ferreira
June 14, 2022
Universitat Rovira i Virgili
Stimuli-responsive Calix[4]pyrrole and Calix[4]arene Based Receptors: from Unimolecular to Dimeric Structures

Chiara Mirabella
September 13, 2022
Universitat Rovira i Virgili
Dynamic Covalent Capsules based on Calix[4]pyrrole scaffolds

 

Features

Our own Prof. Pau Ballester has been recognized with the Chemistry Europe Fellows Class of 2020-2021
https://www.iciq.org/our-own-prof-pau-ballester-has-been-recognized-with-the-chemistry-europe-fellows-class-of-2020-2021/

Projects MAKI and QEE2DUP win 2021 BIST Ignite Awards
https://www.iciq.org/projects-maki-and-qee2dup-win-2021-bist-ignite-awards/